Endocrine Abstracts

The purpose of the present study was to elucidate expressions of ERβ1 and ERβ2 expression in papillary thyroid cancer (PTC). ER β splicing variants expressions were examined on formalin-fixed, paraffin-embedded thyroid tissues from 106 PTCs and 30 nodular thyroid goiters (NTGs) by immunehistochemical methods using Elivision plus two-step system. There was significant difference in the subcellular localization of ERβ1 expression (P<0.001), but not...

ObjectivePlant-derived extracts have long been used to treat Type 2 diabetes mellitus (T2DM), but their effects have not been rigorously investigated at the cellular level in vitro. The aims of the current study were to determine the effects of a virgin isolate of Gymnema sylvestre (GS), designated OSA, on pancreatic β-cell function.Materials and MethodsCell viability was measured by Trypan...